In the Underworld, Vampires are a secret clan of modern aristocratic sophisticates whose mortal enemies are the Lycans (werewolves), a shrewd gang of street thugs who prowl the city's underbelly. No one knows the origin of their bitter blood feud, but the balance of power between them turns even bloodier when a beautiful young Vampire warrior and a newly-turned Lycan with a mysterious past fall in love. Kate Beckinsale and Scott Speedman star in this modern-day, action-packed tale of ruthless intrigue and forbidden passion all set against the dazzling backdrop of a timeless, Gothic metropolis.

A war going on for centuries between vampires and Lycans/werewolves, never seen by humans eyes, until one of the werewolves by the name of Lucian (Michael Sheen) finds out about one human that can bond with vampire blood and Lycans blood, Michael (Scott Speedman). Selene (Kate Beckinsale) is the vampire Death dealer that finds out why the Lycans are following Micheal and falls in love with him. Kraven (Shane Brolly) is the leader of the vampire house after Viktor (Bill Nighy) dies and wants Selene by his side, but she is a wild cat to break.